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Can I read The Utility of Inflammatory and Endothelial Factors in the Prognosis of Severe Dengue on EtoBox?
The Utility of Inflammatory and Endothelial Factors in the Prognosis of Severe Dengue by Srinivasan Sivasubramanian; Sundhar Mohandas; Vidya Gopalan; Velu Vimal Raj; Karthikeyan Govindan; Poovazhagi Varadarajan; Krishnasamy Kaveri; Kunka Mohanram Ramkumar is a Immunology and Microbiology article available to read on EtoBox.
What is The Utility of Inflammatory and Endothelial Factors in the Prognosis of Severe Dengue about?
## Background: Severe dengue is associated with a considerable risk of mortality, and there is currently a lack of appropriate prognostic biomarkers to predict its severity. pathogenesis of severe dengue is characterized by overt inflammation, endothelial activation, and increased vascular permeability. the current study investigates the utility of endothelial, inflammatory, and vascular permeability factors as biomarkers to identify dengue severity, which could improve disease prognosis and management. ## Methods: The dengue-positive subjects were classified based on seropositivity for ns1, igm, and igg. the samples in each group were quantified for basic clinical investigations. the levels of interleukin-6 (il-6), tumor necrosis factor receptor 1 (tnfr1), eotaxin, monocyte chemoattractant protein-1 (mcp-1), monokine induced by interferon-gamma (mig), intercellular adhesion molecule-1 (icam-1), vascular cell adhesion molecule-1 (vcam-1), thrombomodulin, and angiopoietin-2 were estimated in all serum samples using the multiplex bead-based assay. ## Results: Igg seropositive dengue patients showed abnormal laboratory characteristics and severe dengue symptoms. among the studied mark
Who reads The Utility of Inflammatory and Endothelial Factors in the Prognosis of Severe Dengue?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Srinivasan Sivasubramanian; Sundhar Mohandas; Vidya Gopalan; Velu Vimal Raj; Karthikeyan Govindan; Poovazhagi Varadarajan; Krishnasamy Kaveri; Kunka Mohanram Ramkumar
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)