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A phase III trial evaluated the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) compared to piperacillin/tazobactam (PIP/TAZ) in patients with hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP). The study found that IMI/REL was noninferior to PIP/TAZ for 28-day all-cause mortality, with comparable safety profiles. This research supports the use of IMI/REL for treating HABP/VABP, particularly in regions like China where multidrug-resistant infecti

Author
Angel Maurice Montero Sanchez
Language
EN