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This dissertation by Ryan Michael Spengler explores the evolution, regulation, and function of microRNAs (miRNAs), highlighting their role in post-transcriptional gene regulation and their potential origins from transposable elements. It discusses the interaction of long non-coding RNAs as miRNA sponges and presents a tool for designing specific RNA interference triggers. The research contributes to understanding the mechanisms of miRNA emergence and their practical applications in gene silencing.

Author

Bahlibi

Language

EN