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This study evaluated the cytotoxic, genotoxic, antioxidant, and metal chelating activities of 12 hydroxyacetamide derivatives (FP1-FP12) synthesized for their potential as anticancer agents. Brine shrimp lethality assays showed FP2 had the highest cytotoxicity. Genotoxicity assays using Allium cepa root tips found all derivatives caused chromosomal aberrations, with FP1, FP4, FP5, FP11, FP12 showing significant effects compared to cyclophosphamide. Antioxidant assays including DPPH radical scavenging and re
- Author
- supriyo
- Language
- EN