Opening book details…
Can I read Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis on EtoBox?
Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis by Aditya K Panda; Santosh K Panda; Aditya N Sahu; Rina Tripathy; Balachandran Ravindran; Bidyut K Das is a Medicine article available to read on EtoBox.
What is Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis about?
## Background Erythrocyte-associated antigenic polymorphisms or their absence have perhaps evolved in the human population to protect against malarial infection. Studies in various populations consistently demonstrate that blood group 'O' confers resistance against severe falciparum infection. In India, Odisha state has one of the highest incidences of __Plasmodium falciparum__ infection and contributes to the highest number of deaths by falciparum malaria. This study aims to evaluate the relationship between ABO blood group and severe malaria in an adult population at the tertiary care centre in Odisha. ## Methods A total of 353 __P. falciparum__ infected subjects and 174 healthy controls were screened for ABO blood group. Falciparum-infected individuals were categorized as severe malaria and uncomplicated malaria. Severe malaria was further clinically phenotyped into cerebral malaria, non-cerebral severe malaria and multi-organ dysfunction. A meta-analysis was performed to assess the role of ABO blood group in severe malaria. ## Results Frequency of blood group 'B' was significantly higher in patients with severe malaria compared to the uncomplicated cases (P < 0.0001; OR = 4.09)
Who reads Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Aditya K Panda; Santosh K Panda; Aditya N Sahu; Rina Tripathy; Balachandran Ravindran; Bidyut K Das
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2002-; Springer Science and Business Media LLC; Research Square (ISSN 1475-2875)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)