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Maternal Amoxicillin Affects Piglets Colon Microbiota: Microbial Ecology and Metabolomics in a Gut Model by Lorenzo Nissen; Camilla Aniballi; Flavia Casciano; Alberto Elmi; Domenico Ventrella; Augusta Zannoni; Andrea Gianotti; Maria Laura Bacci is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Maternal Amoxicillin Affects Piglets Colon Microbiota: Microbial Ecology and Metabolomics in a Gut Model about?
The first weeks of life represent a crucial stage for microbial colonization of the piglets' gastrointestinal tract. Newborns' microbiota is unstable and easily subject to changes under stimuli or insults. Nonetheless, the administration of antibiotics to the sow is still considered as common practice in intensive farming for pathological conditions in the postpartum. Therefore, transfer of antibiotic residues through milk may occurs, affecting the piglets' colon microbiota. In this study, we aimed to extend the knowledge on antibiotic transfer through milk, employing an in vitro dedicated piglet colon model (MICODE-Multi Unit In vitro Colon Model). The authors' focus was set on the shifts of the piglets' microbiota composition microbiomics (16S r-DNA MiSeq and qPCR-quantitative polymerase chain reaction) and on the production of microbial metabolites (SPME GC/MS-solid phase micro-extraction gas chromatography/mass spectrometry) in response to milk with different concentrations of amoxicillin. The results showed an effective influence of amoxicillin in piglets' microbiota and metabolites production; however, without altering the overall biodiversity. The scenario is that of a limit
Who reads Maternal Amoxicillin Affects Piglets Colon Microbiota: Microbial Ecology and Metabolomics in a Gut Model?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Lorenzo Nissen; Camilla Aniballi; Flavia Casciano; Alberto Elmi; Domenico Ventrella; Augusta Zannoni; Andrea Gianotti; Maria Laura Bacci
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)