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Can I read Placental Growth Factor Testing to Assess Women With Suspected Preeclampsia: A Multicentre, Pragmatic, Stepped-wedge Cluster-randomized Controlled Trial on EtoBox?
Placental Growth Factor Testing to Assess Women With Suspected Preeclampsia: A Multicentre, Pragmatic, Stepped-wedge Cluster-randomized Controlled Trial by Duhig, K.E.; Myers, J.; Seed, P.T.; Sparkes, J.; Lowe, J.; Hunter, R.M.; Shennan, A.H.; Chappell, L.C. is a Medicine article available to read on EtoBox.
What is Placental Growth Factor Testing to Assess Women With Suspected Preeclampsia: A Multicentre, Pragmatic, Stepped-wedge Cluster-randomized Controlled Trial about?
(Lancet. 2019;393:1807–1818) Approximately 3% of singleton pregnancies are affected by preeclampsia, which can be difficult to diagnose as many women are asymptomatic. Hypertension and increased urinary protein excretion are common factors used to establish the diagnosis, but there are challenges in testing and observing both of these features. The pathophysiology of preeclampsia involves angiogenic factors, and low circulating maternal placental growth factor (PlGF) concentrations have been found to be useful in the diagnosis of preeclampsia with high sensitivity and negative predictive value. However, this potential tool for diagnosing preeclampsia should first be tested in a real-world setting to understand both its practical benefits and challenges. This study aimed to determine whether a preeclampsia diagnosis could be more quickly reached in women with suspected preeclampsia by incorporating measurement of the PlGF circulating concentration into an already established clinical management algorithm. The study also investigated the effect of using this diagnostic approach on maternal and perinatal outcomes.
Who reads Placental Growth Factor Testing to Assess Women With Suspected Preeclampsia: A Multicentre, Pragmatic, Stepped-wedge Cluster-randomized Controlled Trial?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Duhig, K.E.; Myers, J.; Seed, P.T.; Sparkes, J.; Lowe, J.; Hunter, R.M.; Shennan, A.H.; Chappell, L.C.
- Publisher
- Lippincott Williams and Wilkins; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Ovid Technologies (Wolters Kluwer Health) (ISSN 0275-665X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)