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Megaloblastic anemia is a group of anemias caused by impaired DNA synthesis, characterized by macroovalocytes in blood smears and megaloblastic hyperplasia in bone marrow. Key causes include deficiencies in folic acid and vitamin B12, often due to dietary issues or malabsorption, leading to ineffective erythropoiesis. Diagnosis involves clinical presentation, laboratory tests for vitamin levels, and possibly the Schilling test to assess malabsorption.

Author

Sneha Poudel

Language

EN