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The Joint Association of Sarcopenia and Frailty with Incidence and Mortality Health Outcomes: a Prospective Study by Petermann-Rocha, Fanny; Gray, Stuart R.; Pell, Jill P.; Ho, Frederick K.; Celis-Morales, Carlos is a Medicine article available to read on EtoBox.
What is The Joint Association of Sarcopenia and Frailty with Incidence and Mortality Health Outcomes: a Prospective Study about?
## Background: Sarcopenia and frailty are strongly associated with disease incidence and mortality. however, there is limited evidence regarding their joint association with health outcomes. this study aimed to investigate the joint association of sarcopenia and frailty with cardiovascular disease (cvd), respiratory disease and cancer incidence and mortality as well as all-cause mortality in middle-aged and older adults in the uk biobank study. ## Methods: 316,980 uk biobank participants were included in this prospective study (53.1% women). sarcopenia was defined according to the ewgsop2 2019. frailty was defined using a modified version of the fried criteria. combined classifications of sarcopenia and frailty were generated with the following seven subgroups derived: i) normal, ii) non-sarcopenic/pre-frail, iii) non-sarcopenic/frail, iv) pre-sarcopenic/pre-frail, v) pre-sarcopenic/frail, vi) sarcopenic/pre-frail, and vii) sarcopenic/frail. no participants had (pre)sarcopenia but not frailty. associations between these exposures and health outcomes (incidence and mortality from cardiovascular and respiratory diseases, cancer, as well as, all-cause mortality) were investigated usin
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- Author
- Petermann-Rocha, Fanny; Gray, Stuart R.; Pell, Jill P.; Ho, Frederick K.; Celis-Morales, Carlos
- Publisher
- Elsevier Science; Elsevier ; Churchill Livingstone; Elsevier BV (ISSN 0261-5614)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)