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Dipeptidyl Peptidase-4 and Endothelial Dysfunction by Maria Valkanioti is a document available to read on EtoBox.
What is Dipeptidyl Peptidase-4 and Endothelial Dysfunction about?
The study investigates the role of dipeptidyl peptidase-4 (sDPP4) in promoting endothelial cell senescence and dysfunction through the PAR2-COX-2-TP axis and NLRP3 inflammasome activation. It details various experimental methods, including cell culture, immunofluorescence, and Western blotting, to assess the effects of sDPP4 on human umbilical vein endothelial cells (HUVEC). The findings suggest that sDPP4 contributes to endothelial dysfunction, which may have implications for cardiovascular health in obese
- Author
- Maria Valkanioti
- Language
- EN