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Sonolysis During Carotid Endarterectomy: Randomised Controlled Trial by David Školoudík, is a book available to read on EtoBox.

What is Sonolysis During Carotid Endarterectomy: Randomised Controlled Trial about?

ABSTRACTnd of the artiCorrespondence to: D SkoloudORCID 0000-0002-2651-3424)OBJECTIVETo evaluate the effectiveness and safety of sonolysisusing a low intensity 2 MHz pulsed wave ultrasoundcopyright, g/10.1136InCAdditional materialis publishedbeam during carotid endarterectomy.To view please visit DESIGNMulticentre, phase 3, double blind, randomised controlled trial.SETTINGAccepted: 17 December 202416 European centres.PARTICIPANTSrisk difference -8.9%,-15% to -2.8%;P=0.004).Sensitivity analysis resulted in a risk ratio for sonolysisof 0.25 (95% C10.11 to 0.56) for ischaemic strokeand 0.23 (0.07 to 0.73) for transient ischaemic attackwithin 30 days. Sonolysis was found to be safe, and 94.4% of patients in the sonolysis group were free from serious adverse events 30 days after the procedure.CONCLUSIONSonolysis was safe for patients undergoing carotidendarterectomy and resulted in a significant reductionin the composite incidence of ischaemic stroke, transient ischaemic attack, and death within 30 days.TRIAL REGISTRATIONClinicaltrials.gov NCT02398734.IntroductionThe possibilities for using therapeutic ultrasound areconstantly expanding. '3 Enhancement of the Iysis of f thrombusisoneoft

Author

David Školoudík,

Published

2025

Language

EN