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What is 5-HT about?

5-HT (serotonin) plays an important role in both the central and peripheral nervous systems. It is synthesized from tryptophan through the enzymes tryptophan hydroxylase and amino acid decarboxylase. Serotonin is released by presynaptic neurons and binds to various 5-HT receptor subtypes to mediate different effects. It is primarily terminated through reuptake by the serotonin transporter protein (SERT). Many antidepressants work by inhibiting SERT, such as selective serotonin reuptake inhibitors (SSRIs), w

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scholify

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EN