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This document reports two cases of squamous cell carcinoma resulting from chronic arsenic exposure in a father and son, both presenting with skin lesions consistent with arsenic keratoses. The patients exhibited various symptoms including hyperkeratotic papules and ulcerated lesions, with histopathology confirming the diagnosis of squamous cell carcinoma. The cases underscore the significant health risks associated with occupational and environmental arsenic exposure, highlighting the need for monitoring an

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EN