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Can I read Pharmacokinetics of Intravenous Omeprazole in Children on EtoBox?
Pharmacokinetics of Intravenous Omeprazole in Children by E. Jacqz-Aigrain; J. Andre; M. Bellaich; C. Faure; J. Navarro; P. Rohrlich; V. Baudouin is a Medicine article available to read on EtoBox.
What is Pharmacokinetics of Intravenous Omeprazole in Children about?
This study was undertaken to define the pharmacokinetics of omeprazole in children and included 13 patients, heterogenous in terms of age (0.3 to 19 years), underlying disease and biological constants, indication of omeprazole administration and associated therapy. The dose administered ranged from 36.9 to 139 mg. 1.73 m 4. The pharmacokinetic parameters of omeprazole were: systemic clearance, 0.23 1. kg -1. h-l; volume of distribution, 0.45 1. kg-1; elimination half life 0.86 h; but were highly variable between individuals. Dosage, differences in hepatic and renal function and associated therapy may contribute to inter-individual variability. Within the range of doses administered, the pharmacokinetic parameters were similar to those reported in adults. The drug has been well tolerated in all children.
Who reads Pharmacokinetics of Intravenous Omeprazole in Children?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- E. Jacqz-Aigrain; J. Andre; M. Bellaich; C. Faure; J. Navarro; P. Rohrlich; V. Baudouin
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0031-6970)
- Published
- 1994
- Language
- EN
- Field
- Medicine (Health Sciences)