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This document compares three genetic disorders caused by trisomies: Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13). In the first trimester, maternal serum screening shows decreased PAPP-A and increased beta-hCG for Down syndrome, and decreased markers for Edwards and Patau syndromes. In the second trimester quad screen, Down syndrome is associated with decreased alpha-fetoprotein and estriol but increased beta-hCG and inhibin A, while Edwards syndrome shows decrea

Author

bob

Language

EN