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Exercise volume load in women with breast cancer: Study protocol for the ABRACE randomized clinical trial by João Saldanha Henkin; Daniela Dornelles Rosa; Alessandra Menezes Morelle; Maira Caleffi; Stephanie Santanna Pinto; Ronei Silveira Pinto is a Medicine article available to read on EtoBox.
What is Exercise volume load in women with breast cancer: Study protocol for the ABRACE randomized clinical trial about?
## Background An increased number of breast cancer patients are challenged by acute and persistent treatment side effects. Oncology guidelines have been establishing physical exercise to counteract several treatment-related toxicities throughout cancer care. However, evidence regarding the optimal dose-response, feasibility, and the minimal resistance exercise volume and/or intensity remains unclear. The ABRACE Study will assess the impact of different resistance training volumes (i.e., single or multiple sets) combined with aerobic exercise on physical and psychological outcomes of breast cancer patients undergoing primary treatment. ## Methods This study is a randomized, controlled, three-armed parallel trial. A total of 84 participants, aged ≥18 years, with breast cancer stages I-III, initiating adjuvant or neoadjuvant chemotherapy (≤50% of sessions completed) will be randomized to multiple sets resistance training plus aerobic training group, single set resistance training plus aerobic training group or control group. Neuromuscular and cancer-related fatigue (primary outcomes), muscle strength, muscle thickness, muscle quality by echo intensity, body composition, cardiorespirat
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- Author
- João Saldanha Henkin; Daniela Dornelles Rosa; Alessandra Menezes Morelle; Maira Caleffi; Stephanie Santanna Pinto; Ronei Silveira Pinto
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)