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Dose Modeling of Noninvasive Image-Guided Breast Brachytherapy in Comparison to Electron Beam Boost and Three-Dimensional Conformal Accelerated Partial Breast Irradiation by Shirin Sioshansi; Mark J. Rivard; Jessica R. Hiatt; Amanda A. Hurley; Yoojin Lee; David E. Wazer is a Medicine article available to read on EtoBox.

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## Purpose: To perform dose modeling of a noninvasive image-guided breast brachytherapy (niigbb) for comparison to electrons and 3dcrt. ## Methods and materials: The novel technology used in this study is a mammography-based, noninvasive breast brachytherapy system whereby the treatment applicators are centered on the planning target volume (ptv) to direct (192)ir emissions along orthogonal axes. to date, three-dimensional dose modeling of niigbb has not been possible because of the limitations of conventional treatment planning systems (tps) to model variable tissue deformation associated with breast compression. in this study, the tps was adapted such that the niigbb dose distributions were modeled as a virtual point source. this dose calculation technique was applied to ct data from 8 patients imaged with the breast compressed between parallel plates in the cranial-caudal and medial-lateral axes. a dose-volume comparison was performed to simulated electron boost and 3dcrt apbi. ## Results: The niigbb ptv was significantly reduced as compared with both electrons and 3dcrt. electron boost plans had a lower d(min) than the niigbb technique but higher v(100), d(90), and d(50). with

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Author

Shirin Sioshansi; Mark J. Rivard; Jessica R. Hiatt; Amanda A. Hurley; Yoojin Lee; David E. Wazer

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2011

Language

EN

Field

Medicine (Health Sciences)