Can I read DNA polymorphisms associated with a new α1-antitrypsin PI Q0 variant (PI Q0riedenburg) on EtoBox?

DNA polymorphisms associated with a new α1-antitrypsin PI Q0 variant (PI Q0riedenburg) by W. Poller; J.-P. Faber; S. Weidinger; K. Olek is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is DNA polymorphisms associated with a new α1-antitrypsin PI Q0 variant (PI Q0riedenburg) about?

A new PIQ0 variant (PIQ0riedenburg) is described; it is caused by a complete deletion of the alpha 1-antitrypsin (alpha 1 AT) gene. The deletion gives rise to four new restriction fragment length polymorphisms (RFLPs) detected with a genomic probe of the 5' region of the gene. Analysis of the RFLPs indicates that the deletion starts immediately upstream of exon Ic. The deletion extends into the 3' flanking region of the gene but does not include the alpha 1 AT-related gene (the PIL gene), which is located 12 kb downstream of the alpha 1 AT gene.

Who reads DNA polymorphisms associated with a new α1-antitrypsin PI Q0 variant (PI Q0riedenburg)?

Author

W. Poller; J.-P. Faber; S. Weidinger; K. Olek

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-6717)

Published

1991

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)