Can I read Correlating Stroke Risk with Non-Invasive Tracing of Brain Blood Dynamic via a Portable Speckle Contrast Optical Spectroscopy Laser Device on EtoBox?

Correlating Stroke Risk with Non-Invasive Tracing of Brain Blood Dynamic via a Portable Speckle Contrast Optical Spectroscopy Laser Device by Huang, Yu Xi; Mahler, Simon; Abedi, Aidin; Tyszka, Julian Michael; Lo, Yu Tung; Lyden, Patrick D.; Russin, Jonathan; Liu, Charles; Yang, Changhuei is a scholarly article available to read on EtoBox.

What is Correlating Stroke Risk with Non-Invasive Tracing of Brain Blood Dynamic via a Portable Speckle Contrast Optical Spectroscopy Laser Device about?

Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests, and comorbidities. A minimally invasive, clinically scalable, and cost-effective way to directly measure cerebral blood flow presents an opportunity. This opportunity has potential to positively impact effective stroke risk assessment prevention and intervention. Physiological changes in the cerebral vascular system, particularly in response to carbon dioxide level changes and oxygen deprivation, such as during breath-holding, can offer insights into stroke risk assessment. However, existing methods for measuring cerebral perfusion reserve, such as blood flow and blood volume changes, are limited by either invasiveness or impracticality. Here, we propose a transcranial approach using speckle contrast optical spectroscopy (SCOS) to non-invasively monitor regional changes in brain blood flow and volume during breath-holding. Our study, conducted on 50 individuals classified into two groups (low-risk and higher-risk for stroke), shows significant d

Author

Huang, Yu Xi; Mahler, Simon; Abedi, Aidin; Tyszka, Julian Michael; Lo, Yu Tung; Lyden, Patrick D.; Russin, Jonathan; Liu, Charles; Yang, Changhuei

Published

2024

Language

EN