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What is Enhanced Detection of mtDNA Deletions about?
Digital PCR methods were found to improve the detection sensitivity and measurement precision of low abundance mtDNA deletions compared to semi-quantitative PCR methods. Digital PCR allows for absolute quantitation of mtDNA deletions, improving precision and reducing assay standard error. MtDNA deletions are a common cause of mitochondrial disorders and have been implicated in aging, neurodegeneration, and cancer. Current methods for detecting mtDNA deletions have limitations including low sensitivity, inab
- Author
- ralli711
- Language
- EN