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What is Glutamatergic System in Depression about?
This review discusses the role of the glutamatergic system in neurodegenerative changes associated with depression, highlighting the potential mechanisms of excitotoxicity and deficits in trophic factors. It examines the relationship between neuronal atrophy in the prefrontal cortex and hippocampus and the impairment of glutamate transporters, as well as the impact of neuroinflammation and BDNF levels on depressive states. The findings suggest that understanding these mechanisms could lead to the developmen
- Author
- William Tillier
- Language
- EN