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Does Intraprostatic Vasopressin Prevent the Transurethral Resection Syndrome? by D.P. Sharma; A.B. Harvey is a Medicine article available to read on EtoBox.

What is Does Intraprostatic Vasopressin Prevent the Transurethral Resection Syndrome? about?

**Objective** To determine whether intraprostatic vasopressin (IPVP) prevents the transurethral resection (TUR) syndrome during prostatectomy. **Patients and methods** The study comprised 36 consecutive patients (mean age 68 years) with prostates clinically assessed as ≥ 20 g who underwent standard transurethral prostatectomy (TURP). Ten units of vasopressin in 0.5 mL were diluted with 9.5 mL isotonic saline and injected into the prostate transrectally before TURP. Blood samples were taken before and immediately after TURP to measure serum sodium concentration and free haemoglobin levels. The TURP irrigant used was cooled, boiled water maintained at 70–80 cmH~2~O pressure during resection. Twenty patients had alcohol added to the irrigant and their breath alcohol assessed at 10‐min intervals during TURP. All patients had their pulse rate, blood pressure and sensorium monitored continuously. Extreme care was taken to avoid and/or identify capsular damage during resection. **Results** The mean weight of tissue resected was 36 g and the mean resection time 24 min. There was no significant change in clinical variables during TURP. In 19 patients the breath alcohol changes were insignif

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Author

D.P. Sharma; A.B. Harvey

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1464-4096)

Published

2000

Language

EN

Field

Medicine (Health Sciences)