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What is AMG 145 Efficacy in Hypercholesterolemia about?

The document summarizes results from a randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of AMG 145, a monoclonal antibody to PCSK9, in combination with statin therapy in patients with hypercholesterolemia. The study found that AMG 145 significantly reduced LDL-C levels after 12 weeks compared to placebo, with reductions ranging from 41-66% depending on dosage. AMG 145 was well tolerated, with no significant safety issues. The results suggest that PCSK9 inhibition via AMG

Author

shashwathh

Language

EN