About this document
AMG 145 Efficacy in Hypercholesterolemia by shashwathh is a document available to read on EtoBox.
The document summarizes results from a randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of AMG 145, a monoclonal antibody to PCSK9, in combination with statin therapy in patients with hypercholesterolemia. The study found that AMG 145 significantly reduced LDL-C levels after 12 weeks compared to placebo, with reductions ranging from 41-66% depending on dosage. AMG 145 was well tolerated, with no significant safety issues. The results suggest that PCSK9 inhibition via AMG
- Author
- shashwathh
- Language
- EN