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The Study of Oxidant-antioxidant Status in Type 2 Diabetes Mellitus by Farhood, H B; Aljabery, R N; Majid, A is a Physics and Astronomy article available to read on EtoBox.

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## Abstract Hyperglycemia is considered a major initiator of oxidative stress which leads to the formation of free radicals and consequently lipid peroxidation occurs, which leads to tissue damage and diabetes mellitus development. Free radicals have been defined as intermediates of some biological redox reactions necessary for the maintenance of life. In presence of a free radical initiator and oxygen they may be oxidized this leading to lipid peroxidation, as it was suggested, might be associated with running out of hydrogen. In particular lipid peroxidation measured as levels of malondialdehyde (MDA). Glutathione (GSH), an intracellular thiol causes the eradication of free radicals or reduction in hydrogen peroxide level on state of oxidative stress. Decrease in the reduced GSH level has been reported in the erythrocyte of diabetics. Decrease in the level of GSH occurs both due to the competition between aldose reductase and glutathione reductase for NADPH, a cofactor, and increased oxidative stress (increased ratio of NADH/NAD). This study was conducted on 60 subjects. Informed consent was obtained from each person who agreed to participate in this study, while the survey was b

Who reads The Study of Oxidant-antioxidant Status in Type 2 Diabetes Mellitus?

Author

Farhood, H B; Aljabery, R N; Majid, A

Publisher

Institute of Physics; IOP Publishing (ISSN 1742-6588)

Published

2019

Language

EN

Field

Physics and Astronomy (Physical Sciences)