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This document discusses myelodysplastic syndromes (MDS), which are a group of acquired stem cell disorders characterized by dysplasia in blood cell lines and an increased risk of acute myeloid leukemia. MDS typically occurs in elderly individuals and presents with anemia, neutropenia, and thrombocytopenia. The pathogenesis involves somatic mutations in stem cells that result in dysfunctional blood cells. MDS are classified according to the FAB and WHO systems based on cell morphology and blast percentage. P

Author

Safi Ullah

Language

EN