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Can I read Recent advances and future developments in PGD on EtoBox?
Recent advances and future developments in PGD by J. C. Harper; D. Wells is a Medicine article available to read on EtoBox.
What is Recent advances and future developments in PGD about?
PGD has now been practised for a decade. The basic techniques currently used involve embryo biopsy, polymerase chain reaction (PCR) and fluorescent in situ hybridization (FISH). Recent advances in molecular diagnostic techniques have included the use of fluorescent PCR, multiplex PCR and whole genome amplification. For cytogenetic analysis, many centres are now using five or more chromosome probes to examine for chromosome abnormalities, sexing and aneuploidy. Future improvements in molecular diagnosis include the use of quantitative PCR, DNA fingerprinting and microarray technology. Developments in methods to analyse chromosomes from a single cell have included interphase chromosome conversion, which has already been clinically applied, and the use of comparative genomic hybridization, which is still being developed. These methods will hopefully enable more accurate and a greater number of diseases to be diagnosed at the single cell level.
Who reads Recent advances and future developments in PGD?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- J. C. Harper; D. Wells
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0197-3851)
- Published
- 1999
- Language
- EN
- Field
- Medicine (Health Sciences)