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Pharmacokinetics of Azithromycin Administered Alone and With Atovaquone in Human Immunodeficiency Virus-Infected Children by Mazim is a document available to read on EtoBox.
To evaluate if atovaquone (ATQ) interacts pharmacokinetically with azithromycin (AZ) in human immu- nodeficiency virus-infected children, 10 subjects (ages, 4 to 13 years) were randomized in a crossover study to receive AZ (5 mg/kg/day) alone (ALONE) or AZ (5 mg/kg/day) and ATQ (30 mg/kg/day) simultaneously (SIM) prior to receiving AZ and ATQ staggered by 12 h. Despite a lack of significant difference in the mean AZ pharmacokinetic parameters, the steady-state values of AZ’s area under the conce
- Author
- Mazim
- Language
- EN