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Characteristics and clinical outcomes of COVID-19 in children: a hospital-based surveillance study in Latin America's hardest-hit city by Daniel Jarovsky; Giuliana de Freitas Fongaro; Renata Mazzotti Zampol; Thales Araújo de Oliveira; Camila Giuliana Almeida Farias; Daniella Gregória Bomfim Prado da Silva; Denis Tadeu Gomes Cavalcante; Sabrina Bortolin Nery; José Cassio de Moraes; Francisco Ivanildo de Oliveira; Flávia Jacqueline Almeida; Marco Aurélio Palazzi Sáfadi is a Medicine article available to read on EtoBox.

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Background: In 2020, Brazil became the epicentre of the coronavirus disease (COVID-19) pandemic in Latin America, resulting in an unparalleled health catastrophe. Nevertheless, comprehensive clinical reports in Brazilian children are not available. Methods: This retrospective, hospital-based, active surveillance study was performed to identify paediatric patients with COVID-19 who presented at a private academic medical centre in a large urban area between March 2020 and March 2021. Clinical and demographic information was analysed for those requiring hospitalization, those with severe illness and those with clinical syndromes. Results: In total, 964 symptomatic cases were evaluated; of these, 17.7% required hospitalization, and 27.5% of hospitalized cases were classified as severe/critical. Acute bronchiolitis and pneumonia were the most common causes of hospitalization among the severe cases. Twenty-seven hospitalized children fulfilled the diagnostic criteria for multi-system inflammatory syndrome (median age 29 months; 85.2% cases were non-severe). A significant co-existing condition was present in 29% of hospitalized children. The risk of hospitalization was higher in children

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Author

Daniel Jarovsky; Giuliana de Freitas Fongaro; Renata Mazzotti Zampol; Thales Araújo de Oliveira; Camila Giuliana Almeida Farias; Daniella Gregória Bomfim Prado da Silva; Denis Tadeu Gomes Cavalcante; Sabrina Bortolin Nery; José Cassio de Moraes; Francisco Ivanildo de Oliveira; Flávia Jacqueline Almeida; Marco Aurélio Palazzi Sáfadi

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)