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## Abstract Eosinophilic esophagitis (EoE) is an allergen‐driven chronic inflammatory condition, characterized by symptoms related to esophageal dysfunction and confirmed histologically by esophageal mucosal eosinophilia. Since its first description in the 1990s, the incidence and prevalence of EoE have been on the rise. It is known to affect all ages of various ethnic backgrounds and both sexes; however, it is most seen in White males. Children with EoE often present with abdominal pain, nausea, vomiting, and failure to thrive, whereas adults with EoE typically present with dysphagia and food impaction. Diagnosis of EoE requires histologic confirmation of elevated esophageal eosinophils in a symptomatic patient, and only after secondary causes have been excluded. Because EoE is a chronic and progressively fibrostenotic disease, treatment goals include resolution of symptoms, induction and maintenance of disease remission, and prevention and possibly reversal of fibrostenotic complications, while minimizing treatment‐related adverse effects and improving quality of life. Treatment strategies include the “3 D's”—drugs, diet, and dilation. Standard drug therapies include proton‐pump

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Author

Joan W. Chen

Publisher

Wiley

Published

2020

Language

EN

Field

Medicine (Health Sciences)