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Can I read Treatment of Adult Rhabdomyosarcoma on EtoBox?
Treatment of Adult Rhabdomyosarcoma by Christian M. Ogilvie; Eileen A. Crawford; Rachel L. Slotcavage; Joseph J. King; Richard D. Lackman; Lee Hartner; Arthur P. Staddon is a Medicine article available to read on EtoBox.
What is Treatment of Adult Rhabdomyosarcoma about?
Objectives: Rhabdomyosarcoma is an exceedingly rare tumor in adults, and standard chemotherapy used for children is much less effective in adults. This study examines short-term outcomes using doxorubicin, ifosfamide, and vincristine for adult rhabdomyosarcoma. Methods: Pathology records were searched for adults (age, Ͼ18) with rhabdomyosarcoma treated at our musculoskeletal tumor center. Treatment involved surgical resection, radiation therapy, and chemotherapy with doxorubicin, ifosfamide, and vincristine. Eleven met inclusion criteria. Mean age was 49 (range: 19 -72). Tumors sites included upper extremity (4 patients), lower extremity (6), and cervix (1). Subtypes were pleomorphic (7), alveolar (1), embryonal (1), and mixed alveolar/embryonal (2). Results: Of the 7 patients with nonmetastatic disease, 6 had no evidence of disease posttreatment, but 1 died of myelodysplastic syndrome after 51 months. Three patients who received neoadjuvant chemotherapy had 100% tumor necrosis. One patient with positive margins scheduled for adjuvant chemotherapy had local recurrence and metastasis within 2 weeks and died 5 months later. Of the 4 patients with metastatic disease on presentation, 1
Who reads Treatment of Adult Rhabdomyosarcoma?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Christian M. Ogilvie; Eileen A. Crawford; Rachel L. Slotcavage; Joseph J. King; Richard D. Lackman; Lee Hartner; Arthur P. Staddon
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)