Can I read Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.) on EtoBox?

Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.) by Krick, Madoka Vera (author);Desmarais, Erick (author);Samaras, Athanasios (author);Guéret, Elise (author);Dimitroglou, Arkadios (author);Pavlidis, Michalis (author);Tsigenopoulos, Costas (author);Guinand, Bruno (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.) about?

## Abstract ## Background In fish, minimally invasive blood sampling is widely used to monitor physiological stress with blood plasma biomarkers. As fish blood cells are nucleated, they might be a source a potential new markers derived from ‘omics technologies. We modified the epiGBS (epiGenotyping By Sequencing) technique to explore changes in genome-wide cytosine methylation in the red blood cells (RBCs) of challenged European sea bass (Dicentrarchus labrax), a species widely studied in both natural and farmed environments. ## Results We retrieved 501,108,033 sequencing reads after trimming, with a mean mapping efficiency of 73.0% (unique best hits). Minor changes in RBC methylome appeared to manifest after the challenge test and a family-effect was detected. Only fifty-seven differentially methylated cytosines (DMCs) close to 51 distinct genes distributed on 17 of 24 linkage groups (LGs) were detected between RBCs of pre- and post-challenge individuals. Thirty-seven of these genes were previously reported as differentially expressed in the brain of zebrafish, most of them involved in stress coping differences. While further investigation remains necessary, few DMC-related genes

Who reads Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.)?

Author

Krick, Madoka Vera (author);Desmarais, Erick (author);Samaras, Athanasios (author);Guéret, Elise (author);Dimitroglou, Arkadios (author);Pavlidis, Michalis (author);Tsigenopoulos, Costas (author);Guinand, Bruno (author)

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)