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The Ayurvedic plant Bacopa Monnieri inhibits inflammatory pathways in the brain by Michelle D. Nemetchek, Andrea A. Stierle, Donald B. Stierle, Diana I. Lurie is a book available to read on EtoBox.

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Abstract 1 1. Introduction 2 2. Materials and Methods 4 2.1 Plant material 4 2.2 Preparation of Extracts 4 2.2.1 Tea 4 2.2.2 Infusion 4 2.2.3 Alkaloid 4 2.2.4 Bacoside A 5 2.3 Cell Culture and microglial stimulation 5 2.4 Cytokine ELISAs 5 2.4 MTS Assay 5 2.5 Enzyme Inhibition assays 5 2.6 Data Analysis 6 3. Results 6 3.1 Concentrations of bacopa extracts 6 3.2 Cytokine release from non-activated N9 microglia 7 3.3 Bacopa inhibits cytokine release in LPS-activated N9 microglia 7 3.4 Bacopa extracts inhibit caspase 1, MMP3, and caspase 3 8 4. Discussion 8 5. Conclusions 10 References 11 Figure 1 14 Figure 2 15 Figure 3 16 Figure 4 17 Figure 5 18 Figure 6 19 2.104-Anxiolytic,2.132—Ayurveda,2.348—Inflammation,2.476—phytochemistry,2.548—signal transduction,Bacopa,inflammation,cytokines,caspases,microglia

Author

Michelle D. Nemetchek, Andrea A. Stierle, Donald B. Stierle, Diana I. Lurie

Language

EN