Can I read Current issues in neonatal screening for cystic fibrosis and implications of the CF gene discovery on EtoBox?

Current issues in neonatal screening for cystic fibrosis and implications of the CF gene discovery by Dr. Philip M. Farrell; Elaine H. Mischler; Norman C. Fost; Benjamin S. Wilfond; Audrey Tluczek; Ronald G. Gregg; W. Theodore Bruns; David J. Hassemer; Ronald H. Laessig is a Medicine article available to read on EtoBox.

What is Current issues in neonatal screening for cystic fibrosis and implications of the CF gene discovery about?

Many questions remain regarding the efficacy, toxicity, and costs of CF neonatal screening. It would be premature, in our opinion, to implement mass population screening of newborns for CF until the benefits and risks have been fully defined, and an adequate and logistically feasible testing system developed and/or highly effective therapy for CF lung disease becomes available. In addition, the ethical issues described herein need to be resolved. This pertains not only to the CF patient but also the heterozygote carrier. These reservations notwithstanding, the discovery of the CF gene should have a favorable impact both directly and indirectly on neonatal screening for the disease. Mutation analysis coupled to IRT testing seems most attractive at this time, at least on a research basis, but primary molecular diagnostic procedures might supervene in the future, particularly if they are financially feasible.

Who reads Current issues in neonatal screening for cystic fibrosis and implications of the CF gene discovery?

Author

Dr. Philip M. Farrell; Elaine H. Mischler; Norman C. Fost; Benjamin S. Wilfond; Audrey Tluczek; Ronald G. Gregg; W. Theodore Bruns; David J. Hassemer; Ronald H. Laessig

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)

Published

1990

Language

EN

Field

Medicine (Health Sciences)