About this Medicine article
Probabilistic risk assessment for milk in dark chocolate, cookies and other baked goods with PAL sold in Canada by Emilie Manny; Sébastien La Vieille; Silvia A. Dominguez; Gregor Kos; Virginie Barrère; Jérémie Théolier; Joseph Touma; Samuel Benrejeb Godefroy is a Medicine article available to read on EtoBox.
The risk of having an allergic reaction in milk-allergic individuals consuming products with precautionary allergen labelling (PAL) for milk has been rarely studied in products such as dark chocolate, cookies, and other baked goods. A probabilistic risk assessment model was developed to estimate potential risks. Milk occurrence and contamination levels were reported in a previous article from our group. Dose-response curves for milk were constructed using values (n = 1078) from published double-blind placebo-controlled food challenges. Canadian consumption data was extracted from a national survey, and a homemade survey involving food-allergic Canadians. Milk eliciting doses (ED) were 0.23 (ED 01 ), 1.34 (ED 05 ), 3.42 (ED 10 ), and 16.3 (ED 25 ) mg of milk protein (Log-Normal distribution). Average exposures, per eating occasion, were 24 mg (dark chocolate), 3.9 mg (baked goods), and 0.20 mg (cookies) of milk proteins. The estimated risk of having a milk-induced allergic reaction by consuming foods with PAL for milk was higher for dark chocolate (16%; 15,881/100,000) than baked goods (3.8%; 3802/100,000) or cookies (0.6%; 646/100,000) in milk-allergic Canadians. Dark chocolate, co
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- Author
- Emilie Manny; Sébastien La Vieille; Silvia A. Dominguez; Gregor Kos; Virginie Barrère; Jérémie Théolier; Joseph Touma; Samuel Benrejeb Godefroy
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Life Sciences)