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Melatonin by Nguyen Nguyen Nguyen is a document available to read on EtoBox.
The study investigates the effects of melatonin on glycolysis and mitochondrial respiration in hepatocellular carcinoma (HCC) cells, revealing that melatonin inhibits glycolysis by downregulating mTORC1 activity and c-Myc expression. Acute treatment with melatonin causes mitochondrial dysfunction and increases reactive oxygen species, while prolonged exposure reduces glycolysis-related proteins such as HK2 and LDHA. These findings suggest that melatonin may serve as an effective adjuvant in liver cancer the
- Author
- Nguyen Nguyen Nguyen
- Language
- EN