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The epidemiology and clinical outcome of hepatitis D virus (delta) infection in Jordan by Ala U. Toukan; Omayma A. Abu-El-Rub; Salwa A. Abu-Laban; Musleh S. Tarawneh; M. Feisal Kamal; Stephen C. Hadler; Krzysztof Krawczynski; Harold S. Margolis; James E. Maynard is a Medicine article available to read on EtoBox.

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The epidemiology and clinical outcome of hepatitis D viral infection in HBsAg-positive acute hepatitis, chronic liver disease, primary hepatocellular carcinoma and the symptomless carrier state was studied in Jordan. The prevalence of hepatitis D viral infection was significantly higher in patients with chronic liver disease (181 79, 23%) and acute hepatitis (17/108, 16%) than in symptomless HBsAg carriers (2/136, 2%). The highest prevalence of hepatitis D viral infection was found in patients with primary hepatocellular carcinoma (10/15, 67%) who were also significantly older than such pa- tients without hepatitis D viral infection. Antihepatitis D virus IgM was detected persistently in 83% of patients with antihepatitis D virus-positive chronic liver disease and transiently in 41% of patients with acute hepatitis. A trend to increased mortality was observed in acute hepatitis D viral superinfection (25%) compared to hepatitis D viral coinfection (0%) and to antihepatitis D virus-negative HBsAg-positive acute hepatitis (4%). In patients with established chronic liver disease, however, neither survival nor histological parameters of disease activity were significantly different in

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Author
Ala U. Toukan; Omayma A. Abu-El-Rub; Salwa A. Abu-Laban; Musleh S. Tarawneh; M. Feisal Kamal; Stephen C. Hadler; Krzysztof Krawczynski; Harold S. Margolis; James E. Maynard
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Elsevier BV; Wiley; Research Square (ISSN 0270-9139)
Published
1987
Language
EN
Field
Medicine (Health Sciences)

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