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Sesquiterpenoids from Homalomena occulta affect osteoblast proliferation, differentiation and mineralization in vitro by Yong-Mei Hu; Chuan Liu; Ka-Wing Cheng; Herman H.-Y. Sung; Lan D. Williams; Zhong-Lin Yang; Wen-Cai Ye is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Sesquiterpenoids from Homalomena occulta affect osteoblast proliferation, differentiation and mineralization in vitro about?
Chemical investigation of rhizomes of Homalomena occulta (Lours) resulted in isolation and identification of two sesquiterpenoids (6,7), and one daucane ester 8, together with five known sesquiterpenoids, oplodiol, oplopanone, homalomenol C, bullatantriol, and 1beta,4beta,7alpha-trihydroxyeudesmane. Their structures were elucidated using 1D and 2D NMR spectroscopic and X-ray analyses. The chloroform extract of this plant and compounds 1-7 were tested in vitro for their activities in stimulating osteoblast (OB) proliferation, differentiation and mineralization. Compounds 1-4 had a stimulative effect on significantly proliferation and differentiation of culture osteoblasts, while the chloroform extract and 1 significantly stimulated mineralization of cultured osteoblasts in vitro.
Who reads Sesquiterpenoids from Homalomena occulta affect osteoblast proliferation, differentiation and mineralization in vitro?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Yong-Mei Hu; Chuan Liu; Ka-Wing Cheng; Herman H.-Y. Sung; Lan D. Williams; Zhong-Lin Yang; Wen-Cai Ye
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0031-9422)
- Published
- 2008
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)