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Can I read A Randomised Controlled Study Shows Supplementation of Overweight and Obese Adults with Lactobacilli and Bifidobacteria Reduces Bodyweight and Improves Well-being on EtoBox?

A Randomised Controlled Study Shows Supplementation of Overweight and Obese Adults with Lactobacilli and Bifidobacteria Reduces Bodyweight and Improves Well-being by Michael, D. R.; Jack, A. A.; Masetti, G.; Davies, T. S.; Loxley, K. E.; Kerry-Smith, J.; Plummer, J. F.; Marchesi, J. R.; Mullish, B. H.; McDonald, J. A. K.; Hughes, T. R.; Wang, D.; Garaiova, I.; Paduchová, Z.; Muchová, J.; Good, M. A.; Plummer, S. F. is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is A Randomised Controlled Study Shows Supplementation of Overweight and Obese Adults with Lactobacilli and Bifidobacteria Reduces Bodyweight and Improves Well-being about?

In an exploratory, block-randomised, parallel, double-blind, single-centre, placebo-controlled superiority study (ISRCTN12562026, funded by Cultech Ltd), 220 Bulgarian participants (30 to 65 years old) with BMI 25–34.9 kg/m^2^ received Lab4P probiotic (50 billion/day) or a matched placebo for 6 months. Participants maintained their normal diet and lifestyle. Primary outcomes were changes in body weight, BMI, waist circumference (WC), waist-to-height ratio (WtHR), blood pressure and plasma lipids. Secondary outcomes were changes in plasma C-reactive protein (CRP), the diversity of the faecal microbiota, quality of life (QoL) assessments and the incidence of upper respiratory tract infection (URTI). Significant between group decreases in body weight (1.3 kg, __p__ < 0.0001), BMI (0.045 kg/m^2^, __p__ < 0.0001), WC (0.94 cm, __p__ < 0.0001) and WtHR (0.006, __p__ < 0.0001) were in favour of the probiotic. Stratification identified greater body weight reductions in overweight subjects (1.88%, __p__ < 0.0001) and in females (1.62%, __p__ = 0.0005). Greatest weight losses were among probiotic hypercholesterolaemic participants (−2.5%, __p__ < 0.0001) alongside a significant between group

Who reads A Randomised Controlled Study Shows Supplementation of Overweight and Obese Adults with Lactobacilli and Bifidobacteria Reduces Bodyweight and Improves Well-being?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Michael, D. R.; Jack, A. A.; Masetti, G.; Davies, T. S.; Loxley, K. E.; Kerry-Smith, J.; Plummer, J. F.; Marchesi, J. R.; Mullish, B. H.; McDonald, J. A. K.; Hughes, T. R.; Wang, D.; Garaiova, I.; Paduchová, Z.; Muchová, J.; Good, M. A.; Plummer, S. F.
Publisher
Springer Science and Business Media LLC; London: Nature Publishing Group; [London]: Springer Nature; Nature Publishing Group; Society for Mining, Metallurgy and Exploration Inc.; Research Square; Springer Nature; Island Press (ISSN 2045-2322)
Published
2020
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

More by Michael, D. R.; Jack, A. A.; Masetti, G.; Davies, T. S.; Loxley, K. E.; Kerry-Smith, J.; Plummer, J. F.; Marchesi, J. R.; Mullish, B. H.; McDonald, J. A. K.; Hughes, T. R.; Wang, D.; Garaiova, I.; Paduchová, Z.; Muchová, J.; Good, M. A.; Plummer, S. F.

Browse all works by Michael, D. R.; Jack, A. A.; Masetti, G.; Davies, T. S.; Loxley, K. E.; Kerry-Smith, J.; Plummer, J. F.; Marchesi, J. R.; Mullish, B. H.; McDonald, J. A. K.; Hughes, T. R.; Wang, D.; Garaiova, I.; Paduchová, Z.; Muchová, J.; Good, M. A.; Plummer, S. F.