About this Biochemistry, Genetics and Molecular Biology article

Eye development and retinal differentiation in an altricial fish species, the senegalese sole ( Solea senegalensis , Kaup 1858) by Ruth Bejarano‐Escobar; Manuel Blasco; Willem J. DeGrip; José Antonio Oyola‐Velasco; Gervasio Martín‐Partido; Javier Francisco‐Morcillo is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

## Abstract We describe the major events in the retinogenesis in an altricial fish species, the Senegalese sole. The major developmental events in the sole retina occurred early after hatching (posthatching day 0, P0). Thus, (1) plexiform layers became recognizable at P1. (2) Proliferative activity disappeared from the central retina at P1, and, as development progressed, became restricted to cells located in the circumferential germinal zone, and to sparse cells dispersed throughout the inner nuclear layer and the outer nuclear layer. (3) Apoptotic cells were sparsely observed, randomly localized in all three nuclear layers of the early posthatching retina from P0 to P4. (4) The first synaptic vesicles were detected at P0 in early postmitotic ganglion cells. However, their appearance in the plexiform layers was delayed until P2. (5) The neurochemical development of most major retinal cell classes occurred between P0 and P5. Thus, although Isl1 immunoreactive ganglion cells were the first to become postmitotic in the vitreal surface of the central retina at P0, the first glutamine synthetase‐expressing Müller cells appeared in the central retina by P5. The onset of expression for o

Author

Ruth Bejarano‐Escobar; Manuel Blasco; Willem J. DeGrip; José Antonio Oyola‐Velasco; Gervasio Martín‐Partido; Javier Francisco‐Morcillo

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 1552-5007)

Published

2010

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)