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Interleukin Protocols (Methods in Molecular Medicine) by O'Neill, Luke A. J.; Bowie, Andrew is a book available to read on EtoBox.
What is Interleukin Protocols (Methods in Molecular Medicine) about?
Interleukins, a family of proteins that regulate immunity and inflammation throughout the body, are also involved in autoimmune disease (rheumatoid arthritis, multiple sclerosis, and asthma); are implicated in such other conditions as cancer, myocardial infarction, and depression; and have value in the diagnosis and prognosis of many diseases. Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced methods for measuring these powerful agents. Their readily reproducible techniques range from the assay of interleukin protein and mRNA-using ELISA, FACS, and RT-PCR-to the study of interleukin signal transduction. Newer techniques are also covered, including the analysis of interleukin gene polymorphisms and the use of cDNA microarrays. Many of the assays are geared to specific pathologies, including breast cancer, depression, psoriasis, Grave's disease, migraine, and myocardial infarction. There are also helpful discussions of the difficulties in measuring interleukins in different biological fluids, such as sputum from asthma patients, peritoneal fluids, synovial fluid from arthritic joints, and cerbrospinal fluid from patients with
- Author
- O'Neill, Luke A. J.; Bowie, Andrew
- Publisher
- Totowa, N.J.: Humana Press
- Published
- 2001
- Language
- EN
- ISBN
- 9781592591466
- Subjects
- Science, Chemistry, Medical
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