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Electroencephalogram versus Magnetic Resonance Imaging Brain as the Initial Investigation of Choice in Neurologically Normal Children with First Afebrile Seizure in India by Jyoti Bagla; Harpreet Kaur; Anu Singhal; Devendra Mishra; Sweta Kumari; Anand Prakash Dubey; Sandhya Soneja is a Medicine article available to read on EtoBox.
What is Electroencephalogram versus Magnetic Resonance Imaging Brain as the Initial Investigation of Choice in Neurologically Normal Children with First Afebrile Seizure in India about?
## Background and Purpose To compare the rates of clinically relevant information provided by electroencephalogram (EEG) and magnetic resonance imaging (MRI) brain in first afebrile seizure (FAS) in children. ## Methods In this prospective randomized controlled trial, neurologically normal children between the age of 2 and 14 years, presenting with first episode of unprovoked, afebrile generalized or partial seizures, were included. Enrolled patients were randomized into two groups. After stabilization, initial workup and management, group I-patients underwent an EEG followed by MRI, whereas group II-patients underwent an initial MRI brain followed by an EEG. The patients were followed up after results of both the investigations and then every 3 months for seizure recurrence. The primary outcome was the proportion of investigations, providing clinically relevant information. The secondary outcomes were to determine the etiological diagnosis of FAS and record adverse events associated with EEG and MRI. ## Results Out of 170 enrolled patients, 52 patients (61.2%) in initial EEG group and 53 patients (70.6%) in initial MRI group had abnormal results on first investigation. An etiologi
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- Author
- Jyoti Bagla; Harpreet Kaur; Anu Singhal; Devendra Mishra; Sweta Kumari; Anand Prakash Dubey; Sandhya Soneja
- Publisher
- Korean Epilepsy Society
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)