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Immunosuppressive Drugs in Cardiology by doc.MUDr.Ivan Málek, CSc., MUDr.Markéta Hegarová is a scholarly article available to read on EtoBox.

What is Immunosuppressive Drugs in Cardiology about?

The aim of the article is to provide a basic information about immunosuppressive drugs and their use in cardiology. The most frequent indication for immunosuppressants is the prevention and treatment of rejection after cardiac transplantation. Drugs with antiproliferative effect (m-TOR inhibitors) are also the most frequent ones used in drug-eluting coronary stents, decreasing significanty the rate of restenosis. Another form of coronary proliferative syndrome, chronic rejection after cardiac transplantation, can be effectively influenced with systemic aplication of these drugs. Another indication for immunosuppressives present some types of myocarditis and inflammatory cardiomyopathies. Calcineurin inhibitors may be useful in the prevention of injury after myocardial reperfusion, but this approach in still experimental.

Author

doc.MUDr.Ivan Málek, CSc., MUDr.Markéta Hegarová

Published

2011