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PD-L1 Amplification in Oral SCC Study by quitianstephanie is a document available to read on EtoBox.
What is PD-L1 Amplification in Oral SCC Study about?
The study investigates PD-L1 gene amplification and protein expression in oral squamous cell carcinoma (OSCC), finding PD-L1 expression in 45% of cases and gene amplification in 19%. The presence of PD-L1 is associated with a higher risk of nodal metastasis and poorer overall survival. The authors suggest including PD-L1 copy number status in future clinical trials targeting the PD-1/PD-L1 axis for immunotherapy strategies.
- Author
- quitianstephanie
- Language
- EN