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Can I read Treatment-Related Pneumonitis and Acute Esophagitis in Non-Small-Cell Lung Cancer Patients Treated With Chemotherapy and Helical Tomotherapy: In Regard to Song et al. on EtoBox?
Treatment-Related Pneumonitis and Acute Esophagitis in Non-Small-Cell Lung Cancer Patients Treated With Chemotherapy and Helical Tomotherapy: In Regard to Song et al. by Minesh P. Mehta; Deepak Khuntia is a Medicine article available to read on EtoBox.
What is Treatment-Related Pneumonitis and Acute Esophagitis in Non-Small-Cell Lung Cancer Patients Treated With Chemotherapy and Helical Tomotherapy: In Regard to Song et al. about?
In a recently published article by Song et al. (1), the authors present a retrospective review of 37 consecutive patients treated definitively with helical tomotherapy for unresectable non-small-cell lung cancer (NSCLC). This is one of an emerging series of studies evaluating dose escalation for treatment of NSCLC, although we published a more definitive clinical trial earlier (2). What is unique in the study by Song et al. (1) is that patients were treated concurrently with chemotherapy, and several were treated with hypofractionated radiation therapy, and that the study included patients with poor performance status as well as those with involved supraclavicular nodes, resulting in very large planning target volumes (PTVs), a patient group that is typically excluded from most clinical trials (by the authors' own admission). Despite selecting a cohort with such advanced disease and poor PS, the authors present very impressive 2-year local control and survival rates of 63% and 56%, respectively. However, there was a notable rate of treatment-related deaths (11%). That important paper raises several issues that need to be considered as we apply advanced technologies in managing NSCL
Who reads Treatment-Related Pneumonitis and Acute Esophagitis in Non-Small-Cell Lung Cancer Patients Treated With Chemotherapy and Helical Tomotherapy: In Regard to Song et al.?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Minesh P. Mehta; Deepak Khuntia
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)