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Seroconversion following the first, second, and third dose of SARS-CoV-2 vaccines in immunocompromised population: a systematic review and meta-analysis by Mohammad-Mehdi Mehrabi Nejad; Parnian Shobeiri; Hojat Dehghanbanadaki; Mohammadreza Tabary; Armin Aryannejad; Abdolkarim Haji Ghadery; Mahya Shabani; Fatemeh Moosaie; SeyedAhmad SeyedAlinaghi; Nima Rezaei is a Medicine article available to read on EtoBox.
What is Seroconversion following the first, second, and third dose of SARS-CoV-2 vaccines in immunocompromised population: a systematic review and meta-analysis about?
## Background: Immunocompromised (ic) patients are at higher risk of more severe covid-19 infections than the general population. special considerations should be dedicated to such patients. we aimed to investigate the efficacy of covid-19 vaccines based on the vaccine type and etiology as well as the necessity of booster dose in this high-risk population. ## Materials and methods: We searched pubmed, web of science, and scopus databases for observational studies published between june 1st, 2020, and september 1st, 2021, which investigated the seroconversion after covid-19 vaccine administration in adult patients with ic conditions. for investigation of sources of heterogeneity, subgroup analysis and sensitivity analysis were conducted. statistical analysis was performed using r software. ## Results: According to the preferred reporting items for systematic reviews and meta-analyses, we included 81 articles in the meta-analysis. the overall crude prevalence of seroconversion after the first (n: 7460), second (n: 13,181), and third (n: 909, all population were transplant patients with mrna vaccine administration) dose administration was 26.17% (95% ci 19.01%, 33.99%, i = 97.1%), 57.
Who reads Seroconversion following the first, second, and third dose of SARS-CoV-2 vaccines in immunocompromised population: a systematic review and meta-analysis?
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- Author
- Mohammad-Mehdi Mehrabi Nejad; Parnian Shobeiri; Hojat Dehghanbanadaki; Mohammadreza Tabary; Armin Aryannejad; Abdolkarim Haji Ghadery; Mahya Shabani; Fatemeh Moosaie; SeyedAhmad SeyedAlinaghi; Nima Rezaei
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)