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Expression Enhancement of Trastuzumab in CHO Cells by Heidy Uchiha is a document available to read on EtoBox.
What is Expression Enhancement of Trastuzumab in CHO Cells about?
The research article discusses the enhancement of trastuzumab expression in CHO cells through codon optimization and promoter selection. It emphasizes the importance of genetic optimizations, including the use of specific promoters and expression vectors, to improve the yield of monoclonal antibodies. The study presents the development of a codon optimization algorithm for trastuzumab genes and its application in cloning these genes into mammalian expression vectors for improved protein production.
- Author
- Heidy Uchiha
- Language
- EN