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Effect of Radiotherapy on Expanders and Permanent Implants in Immediate Breast Reconstruction: Long-term Surgical and Patient-reported Outcomes in a Large Multicentre Cohort by Hannah Coudé Adam; Axel Frisell; Yihang Liu; Helena Sackey; Ira Oikonomou; Ann-Charlot Docherty Skogh; Jan Frisell; Jana de Boniface is a Medicine article available to read on EtoBox.

What is Effect of Radiotherapy on Expanders and Permanent Implants in Immediate Breast Reconstruction: Long-term Surgical and Patient-reported Outcomes in a Large Multicentre Cohort about?

## Abstract ## Background Current evidence for the effects of radiotherapy (RT) on implant-based immediate breast reconstruction (IBR) is limited by short follow-up and lack of patient-reported outcomes (PROs). It is central to integrate long-term comprehensive outcome data into the preoperative decision-making process. The aim of the present study was to determine long-term surgical outcomes and PROs in relation to RT after implant-based IBR. ## Methods This was a longitudinal cohort study of PRO data obtained in surveys conducted in 2012 and 2020 using the BREAST-Q questionnaire. All women undergoing therapeutic mastectomy and implant-based IBR between 1 January 2007 and 31 December 2011 at four breast centres in Stockholm, Sweden, were identified. The endpoint was implant removal owing to surgical complications or patient preference. ## Results Median follow-up was 120 (range 1–171) months. After 754 IBRs in 729 women, implant removal occurred in 128 (17 per cent): 34 of 386 (8.8 per cent) in the no-RT group, 20 of 64 (31.3 per cent) in the group with previous RT, and 74 of 304 (24.3 per cent) in the postoperative RT group (P < 0.001). Implant removal was because of surgical com

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Author

Hannah Coudé Adam; Axel Frisell; Yihang Liu; Helena Sackey; Ira Oikonomou; Ann-Charlot Docherty Skogh; Jan Frisell; Jana de Boniface

Publisher

Oxford University Press (OUP)

Published

2021

Language

EN

Field

Medicine (Health Sciences)