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Association of adenoma and focal nodular hyperplasia: experience of a single French academic center by Christophe Laurent; Hervé Trillaud; Sébastien Lepreux; Charles Balabaud; Paulette Bioulac-Sage is a Medicine article available to read on EtoBox.

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BACKGROUND: We report our experience of the simultaneous occurrence of adenoma and focal nodular hyperplasia (FNH). Liver cell adenoma together with FNH was found in five out of 30 cases of "multiple benign hepatocytic nodules" collected in our files of the Department of Pathology of the University Hospital of Bordeaux, during the last 12 years. All five cases were women on oral contraceptives. In all cases, the reason for surgery was the discovery, by imaging techniques, of an adenoma (4 cases) or of an unidentified benign tumor, possibly an adenoma. RESULTS: Four cases of FNH were discovered by imaging techniques, prior to surgery. Additional small nodules were diagnosed either during surgery or during the slicing of the specimen in 3 cases. Adenoma and the FNH cases identified by imaging techniques were confirmed as such by light microscopy. Some small nodules could not be categorized with certainty because they contained biliary structures without ductular reaction. In one case, the non-nodular liver was abnormal around the area in which there were multiple nodules: there was approximation of portal tracts with portal and hepatic venous thromboses, and portal tract remnants wit

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Author

Christophe Laurent; Hervé Trillaud; Sébastien Lepreux; Charles Balabaud; Paulette Bioulac-Sage

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, c2002-2012.; Springer Science and Business Media LLC (ISSN 1476-5926)

Published

2003

Language

EN

Field

Medicine (Health Sciences)