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Mapping Symptoms to Brain Networks with the Human Connectome by Michael D. Fox is a Medicine article available to read on EtoBox.

What is Mapping Symptoms to Brain Networks with the Human Connectome about?

he study of focal brain lesions has traditionally been used to map neurologic symptoms to specific regions; however, many neurologic and psychiatric symptoms correspond more closely to networks of connected regions. A new resource termed the human connectome, derived from functional neuroimaging of thousands of healthy persons, provides a map of these brain connections. With the use of the connectome, lesions in different locations that cause the same symptom can be linked to common networks in ways not previously possible. This approach, termed lesion network mapping, is being applied to lesions associated with a variety of neuropsychiatric symptoms, including hallucinations, delusions, abnormal movements, pain, coma, and cognitive or social dysfunction (see the interactive graphic, available with the full text of this article at NEJM.org). Connectome localizations may expose new treatment targets for patients with complex neurologic and psychiatric symptoms. To appreciate this new approach to symptom localization, it is helpful to understand the evolution of classic lesion localization, functional imaging, the human brain connectome, and the analytic method of lesion network mapp

Who reads Mapping Symptoms to Brain Networks with the Human Connectome?

Author

Michael D. Fox

Publisher

Massachusetts Medical Society

Published

2018

Language

EN

Field

Medicine (Health Sciences)