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Self-assembled hydrogel nanoparticles were synthesized from carboxymethylated curdlan substituted with sulfonylurea groups to form a hydrophobic core. The nanoparticles were characterized and their ability to deliver an anti-cancer drug and specifically interact with liver cancer cells was examined. The drug release rate could be controlled and liver cells strongly interacted with nanoparticles conjugated with a ligand for the liver cell receptors.

Author

Ppa Gpat Amit

Language

EN